Dihexa 10 mg

Dihexa for research: identity and specifications

Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, CAS 1401708-83-5) is a synthetic peptide derivative developed for laboratory evaluation of hepatocyte growth factor (HGF) signaling pathways. Supplied as a 10 mg vial of lyophilized powder, with no declared fillers, carriers or excipients, made by solid-phase peptide synthesis and purified to analytical standards, at ≥98% purity by HPLC with the lot-specific value reported on the certificate of analysis.

Scientific background

In experimental models, Dihexa is investigated for its interaction with the HGF/c-Met signaling pathway, in in vitro models of synaptic plasticity and neurogenesis, and for neuroprotection in rodent models of central nervous system tissue repair.

Preclinical literature uses it as a reference compound in studies of neurotrophism and synaptogenesis, always under controlled bench conditions and without extrapolating results to human or veterinary use.

• Hepatocyte growth factor (HGF/c-Met) signaling in in vitro assays
• Synaptic plasticity and neurogenesis in research models
• Neuroprotection in experimental tissue-repair models
• Synaptogenesis in neuronal cultures

Technical specifications

Analytical quality and chain of custody

Every lot of Dihexa is synthesized in registered facilities, with independent analytical verification by third-party laboratories and full chain-of-custody documentation. The certificate of analysis (COA) for each lot can be reviewed before purchase, recording HPLC purity and the other quality-control parameters used to release the material.

Reconstitution and laboratory handling

As a bench procedure, the lyophilized vial is reconstituted with a known volume of a suitable solvent, added along the inner wall of the vial, followed by gentle swirling until fully dissolved, without vigorous shaking. The reconstituted solution should be kept refrigerated and protected from light, and used in controlled assays within the stability period validated by the laboratory. Handling must be performed only by qualified personnel, in a bench environment suitable for in vitro experimentation, with lot number and storage conditions documented according to good laboratory practice.

Frequently asked questions

What is the purity of the Dihexa supplied?

≥98% by HPLC, with the lot-specific value reported on the certificate of analysis (COA).

Are Dihexa, PNB-0408 and N-hexanoic-Tyr-Ile-(6) aminohexanoic amide the same compound?

Yes, they are synonyms for the same molecule, identified by PubChem CID 129010512 and CAS 1401708-83-5.

How should the compound be stored?

In a dry place, protected from light and moisture.

Does the certificate of analysis come with the lot?

Yes, every lot has a matching COA that can be verified before purchase using the button on this page.

Who can purchase Dihexa?

Sales are restricted to qualified researchers and institutions, for laboratory use only, as detailed in the research-use-only notice on this page.

See the peptide reference guide, the page on how every lot is tested by HPLC and COA and the molecular structure in the PubChem database.

Research use only (RUO). This material is supplied for in vitro laboratory research only. It is not a drug, dietary supplement or cosmetic, and it is not intended for human or veterinary use, or for the diagnosis or treatment of any condition. Sales are restricted to researchers and institutions.