Thymosin Alpha-1 10 mg

Thymosin Alpha-1 for research: identity and specifications

Thymosin Alpha-1 (thymalfasin, CAS 62304-98-7) is a synthetic 28-amino-acid, N-acetylated peptide originally described in thymus extracts and studied as a modulator of immune signaling. Supplied as a 10 mg vial of lyophilized powder, with no fillers, carriers or excipients, at ≥98% purity by HPLC, with the lot-specific value reported on the certificate of analysis.

Scientific background

In experimental models, thymosin alpha-1 is investigated for its interaction with Toll-like receptors (TLRs) on dendritic cells, and for T-cell maturation and cytokine production in immune cell cultures. These in vitro assays allow researchers to examine pattern-recognition pathways and the activation of innate and adaptive immunity.

Preclinical literature also uses the peptide in animal models of infection and tumor immunology, always under controlled bench conditions and without extrapolating results to human or veterinary use. Thymalfasin has been the subject of clinical studies and is regulated as a drug in some jurisdictions; the material supplied here is a research reagent and is not that product.

• Toll-like receptor (TLR) signaling in dendritic cells
• T-cell maturation and differentiation in culture
• Cytokine production in in vitro immune activation models
• Preclinical animal models of infection and tumor immunology

Technical specifications

Analytical quality and chain of custody

Every lot of Thymosin Alpha-1 is synthesized in registered facilities, with independent analytical verification by third-party laboratories and full chain-of-custody documentation. The certificate of analysis (COA) for each lot can be reviewed before purchase, recording HPLC purity and the other quality-control parameters used to release the material.

Reconstitution and laboratory handling

As a bench procedure, the lyophilized vial is reconstituted with a known volume of a suitable solvent, added along the inner wall of the vial, followed by gentle swirling until fully dissolved, without vigorous shaking. The reconstituted solution should be kept refrigerated and protected from light, and used in controlled assays within the stability period validated by the laboratory. Handling must be performed only by qualified personnel, in a bench environment suitable for in vitro experimentation, with lot number and storage conditions documented according to good laboratory practice.

Frequently asked questions

What is the purity of the Thymosin Alpha-1 supplied?

≥98% by HPLC, with the lot-specific value reported on the certificate of analysis (COA).

Are Thymosin Alpha-1, thymosin alpha 1 and thymalfasin the same compound?

Yes, they are synonyms for the same 28-amino-acid peptide, identified by CAS number 62304-98-7 and PubChem CID 16130571.

How should the compound be stored?

At -20 °C, protected from light and moisture, as a lyophilized powder until reconstitution.

Does the certificate of analysis come with the lot?

Yes, every lot has a matching COA that can be verified before purchase using the button on this page.

Who can purchase Thymosin Alpha-1?

Sales are restricted to qualified researchers and institutions, for laboratory use only, as detailed in the research-use-only notice on this page.

See the peptide reference guide, the page on how every lot is tested by HPLC and COA and the molecular structure in the PubChem database.

Research use only (RUO). This material is supplied for in vitro laboratory research only. It is not a drug, dietary supplement or cosmetic, and it is not intended for human or veterinary use, or for the diagnosis or treatment of any condition. Sales are restricted to researchers and institutions.