Tesamorelin 10 mg

Tesamorelin for research: identity and specifications

Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH), a 44-amino-acid chain carrying an N-terminal trans-3-hexenoyl modification that gives it greater stability than the native molecule. Supplied as a 10 mg vial of lyophilized powder, with no fillers, carriers or excipients, at ≥98% purity by HPLC, with the lot-specific value reported on the certificate of analysis.

Scientific background

In experimental models, GHRH analogs such as Tesamorelin are investigated for their interaction with GHRH receptors on pituitary cells and for pulsatile growth hormone (GH) release in cell culture and in animal models, including studies of the GH/IGF-1 axis.

The N-terminal modification protects the peptide from rapid cleavage by dipeptidyl peptidase-IV, and this stability makes it a useful reference compound in receptor-binding and peptide-degradation assays, always under controlled bench conditions and without extrapolating results to human or veterinary use.

• GHRH receptor interaction in in vitro assays
• Pulsatile GH release in experimental models
• GH/IGF-1 axis signaling in preclinical studies
• Peptide stability and N-terminal modification in degradation assays

Technical specifications

Analytical quality and chain of custody

Every lot of Tesamorelin is synthesized in registered facilities, with independent analytical verification by third-party laboratories and full chain-of-custody documentation. The certificate of analysis (COA) for each lot can be reviewed before purchase, recording HPLC purity and the other quality-control parameters used to release the material.

Reconstitution and laboratory handling

As a bench procedure, the lyophilized vial is reconstituted with a known volume of a suitable solvent, added along the inner wall of the vial, followed by gentle swirling until fully dissolved, without vigorous shaking. The reconstituted solution should be kept refrigerated and protected from light, and used in controlled assays within the stability period validated by the laboratory. Handling must be performed only by qualified personnel, in a bench environment suitable for in vitro experimentation, with lot number and storage conditions documented according to good laboratory practice.

Frequently asked questions

What is the purity of the Tesamorelin supplied?

≥98% by HPLC, with the lot-specific value reported on the certificate of analysis (COA).

What is the difference between Tesamorelin and other GHRH analogs?

Tesamorelin is a 44-amino-acid GHRH analog with an N-terminal trans-3-hexenoyl group, which distinguishes it structurally from shorter GHRH fragments. It is identified by PubChem CID 16137828.

How should the compound be stored?

At -20 °C, protected from light and moisture, as a lyophilized powder until reconstitution.

Does the certificate of analysis come with the lot?

Yes, every lot has a matching COA that can be verified before purchase using the button on this page.

Who can purchase Tesamorelin?

Sales are restricted to qualified researchers and institutions, for laboratory use only, as detailed in the research-use-only notice on this page.

See the peptide reference guide, the page on how every lot is tested by HPLC and COA and the molecular structure in the PubChem database.

Research use only (RUO). This material is supplied for in vitro laboratory research only. It is not a drug, dietary supplement or cosmetic, and it is not intended for human or veterinary use, or for the diagnosis or treatment of any condition. Sales are restricted to researchers and institutions.