Ipamorelin 5–10 mg

Ipamorelin for research: identity and specifications

Ipamorelin (NNC 26-0161) is a synthetic pentapeptide of sequence Aib-His-D-2-Nal-D-Phe-Lys-NH₂ (CAS 170851-70-4), developed as a selective agonist of the growth hormone secretagogue receptor (GHS-R1a). Supplied as a 5 mg or 10 mg vial, lyophilized powder, with no fillers, carriers or excipients, at ≥98% purity by HPLC and the lot-specific value reported on the certificate of analysis.

Scientific background

Ipamorelin binds the GHS-R1a (ghrelin) receptor and is used in experimental models as a reference secretagogue to study receptor-specific signaling and pulsatile growth hormone release in pituitary cell culture. Preclinical studies describe a selective profile relative to older growth hormone-releasing peptides, which makes it a useful comparator in selectivity assays.

The literature includes cell-based assays and rodent models of the somatotropic axis, always under controlled bench conditions and without extrapolating results to human or veterinary use.

• Selective interaction with the GHS-R1a receptor
• Models of pulsatile growth hormone secretion in pituitary cells
• Comparative selectivity studies against other secretagogues
• Structure-activity work on non-natural amino acid peptides (Aib, D-2-Nal)

Technical specifications

Analytical quality and chain of custody

Every lot of Ipamorelin is synthesized in registered facilities, with independent analytical verification by third-party laboratories and full chain-of-custody documentation. The certificate of analysis (COA) for each lot can be reviewed before purchase, recording HPLC purity and the other quality-control parameters used to release the material.

Reconstitution and laboratory handling

As a bench procedure, the lyophilized vial is reconstituted with a known volume of a suitable solvent, added along the inner wall of the vial, followed by gentle swirling until fully dissolved, without vigorous shaking. The reconstituted solution should be kept refrigerated and protected from light, and used in controlled assays within the stability period validated by the laboratory. Handling must be performed only by qualified personnel, in a bench environment suitable for in vitro experimentation, with lot number and storage conditions documented according to good laboratory practice.

Frequently asked questions

What is the purity of the Ipamorelin supplied?

≥98% by HPLC, with the lot-specific value reported on the certificate of analysis (COA).

Are Ipamorelin and NNC 26-0161 the same compound?

Yes, they are synonyms for the same pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH₂), identified by PubChem CID 9831659 and CAS 170851-70-4.

How should the compound be stored?

At -20 °C, protected from light and moisture, as a lyophilized powder until reconstitution.

Does the certificate of analysis come with the lot?

Yes, every lot has a matching COA that can be verified before purchase using the button on this page.

Who can purchase Ipamorelin?

Sales are restricted to qualified researchers and institutions, for laboratory use only, as detailed in the research-use-only notice on this page.

See the peptide reference guide, the page on how every lot is tested by HPLC and COA, and the molecular structure in the PubChem database.

Research use only (RUO). This material is supplied for in vitro laboratory research only. It is not a drug, dietary supplement or cosmetic, and it is not intended for human or veterinary use, or for the diagnosis or treatment of any condition. Sales are restricted to researchers and institutions.