Selank 10 mg

Selank for research: identity and specifications

Selank is a synthetic heptapeptide with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro, an analog derived from the immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg) extended with a Pro-Gly-Pro tail. Supplied as a 10 mg vial of lyophilized powder, with no fillers, carriers or excipients, at ≥98% purity by HPLC, with the lot-specific value reported on the certificate of analysis.

Scientific background

The Pro-Gly-Pro extension was designed to slow enzymatic degradation of the tuftsin core, and Selank is therefore used in research on neuropeptide signaling and peptide stability. In experimental models, it is investigated for interaction with GABAergic pathways and for effects on the expression of neurotrophic factors and on the enzymatic breakdown of enkephalins.

Preclinical literature employs Selank in rodent behavioral models and in cell culture studies of neuropeptide regulation, always under controlled bench conditions and without extrapolating results to human or veterinary use.

• Tuftsin-derived neuropeptide signaling in vitro
• GABAergic pathway modulation in experimental models
• Enkephalin degradation and peptide stability assays
• Neurotrophic factor expression in rodent models

Technical specifications

Analytical quality and chain of custody

Every lot of Selank is synthesized in registered facilities, with independent analytical verification by third-party laboratories and full chain-of-custody documentation. The certificate of analysis (COA) for each lot can be reviewed before purchase, recording HPLC purity and the other quality-control parameters used to release the material.

Reconstitution and laboratory handling

As a bench procedure, the lyophilized vial is reconstituted with a known volume of a suitable solvent, added along the inner wall of the vial, followed by gentle swirling until fully dissolved, without vigorous shaking. The reconstituted solution should be kept refrigerated and protected from light, and used in controlled assays within the stability period validated by the laboratory. Handling must be performed only by qualified personnel, in a bench environment suitable for in vitro experimentation, with lot number and storage conditions documented according to good laboratory practice.

Frequently asked questions

What is the purity of the Selank supplied?

≥98% by HPLC, with the lot-specific value reported on the certificate of analysis (COA).

Is Selank the same as tuftsin?

No. Tuftsin is the endogenous tetrapeptide Thr-Lys-Pro-Arg, while Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) built on that sequence and identified by PubChem CID 11765600.

How should the compound be stored?

At -20 °C, protected from light and moisture, as a lyophilized powder until reconstitution.

Does the certificate of analysis come with the lot?

Yes, every lot has a matching COA that can be verified before purchase using the button on this page.

Who can purchase Selank?

Sales are restricted to qualified researchers and institutions, for laboratory use only, as detailed in the research-use-only notice on this page.

See the peptide reference guide, the page on how every lot is tested by HPLC and COA and the molecular structure in the PubChem database.

Research use only (RUO). This material is supplied for in vitro laboratory research only. It is not a drug, dietary supplement or cosmetic, and it is not intended for human or veterinary use, or for the diagnosis or treatment of any condition. Sales are restricted to researchers and institutions.