Bundle Prime

Bundle Prime for research: composition

Bundle Prime is a kit of three individual vials of lyophilized powder: Thymosin Alpha-1 (10 mg), NAD+ (500 mg) and MOTS-c (10 mg). Each component has ≥98% purity by HPLC and its own COA for every lot.

Included compounds

Thymosin Alpha-1 (10 mg)

Synthetic 28-amino-acid peptide corresponding to a sequence found in thymic peptides. It is investigated in in vitro models for T-lymphocyte maturation and signaling (CAS 62304-98-7; PubChem CID 16130571).

NAD+ (500 mg)

Nicotinamide adenine dinucleotide, a central coenzyme of cellular redox metabolism. In in vitro assays and rodents it is studied in mitochondrial redox reactions, sirtuins and PARP-dependent DNA repair pathways (CAS 53-84-9; PubChem CID 5892).

MOTS-c (10 mg)

Mitochondrial peptide of 16 amino acids (MRWQEMGYIFYPRKLR), encoded by a short open reading frame in the mitochondrial 12S rRNA gene. In cell cultures and rodents it is investigated for metabolic homeostasis and AMPK activation (CAS 1627580-64-6; PubChem CID 146675088).

Research rationale for the set

The set brings together a thymic peptide, a redox coenzyme and a mitochondrial peptide, covering three axes of cellular aging at the bench: immunosenescence and thymic function, NAD+/NADH metabolism and mitochondrial-genome-derived signaling. Data come from cell cultures and rodents, without extrapolation to humans.

Analytical quality and COA

Every component of Bundle Prime is supplied at ≥98% purity by HPLC with a certificate of analysis (COA) for each lot, backed by independent third-party analytical verification and chain-of-custody documentation. The COA can be reviewed before purchase.

Storage and handling

Store all vials at -20 °C, protected from light and moisture, in the original sealed packaging. As a bench procedure, each lyophilized vial is reconstituted separately with a known volume of a suitable solvent, added along the inner wall and gently swirled, without vigorous shaking. Handling is restricted to qualified personnel in a laboratory setting, with the lot number recorded.

Frequently asked questions

Why does Bundle Prime combine these three compounds?

Because together they cover immune function, redox metabolism and mitochondrial signaling in cellular aging research. Each is also available individually in the catalog.

What is the purity and how can I check the COA?

≥98% by HPLC for each component, with the lot-specific value reported on the COA of each vial, which can be reviewed before purchase.

Who can purchase this material?

Sales are restricted to qualified researchers and institutions, for laboratory use only, as stated in the research-use-only notice on this page.

See the peptide reference guide, the page on how every lot is tested by HPLC and COA and the molecular structure of NAD+ in the PubChem database.

Research use only (RUO). This material is supplied for in vitro laboratory research only. It is not a drug, dietary supplement or cosmetic, and it is not intended for human or veterinary use, or for the diagnosis or treatment of any condition. Sales are restricted to researchers and institutions.