Vesugen 20 mg

Vesugen for research: identity and specifications

Vesugen is a short synthetic peptide bioregulator of the Khavinson class, a tripeptide with the sequence L-Lys-L-Glu-L-Asp (KED), originally described from analysis of vascular tissue extracts. Supplied as a 20 mg vial of lyophilized powder, with no fillers, carriers or excipients, at ≥98% purity by HPLC, with the lot-specific value reported on the certificate of analysis.

Scientific background

Short peptides of this class are investigated for a hypothesized ability to interact with DNA and to modulate gene expression in a tissue-specific way. In experimental models, Vesugen is examined for endothelial cell signaling and for the activity of transcription factors related to angiogenesis.

The literature is largely preclinical and in vitro, and the compound is used in basic studies of vascular cell biology and tissue aging, always under controlled bench conditions and without extrapolating results to human or veterinary use.

• Vascular short-peptide bioregulators of the Khavinson class
• Endothelial cell signaling in experimental models
• Transcription-factor activity related to angiogenesis
• Peptide-DNA interaction hypotheses in vitro

Technical specifications

Analytical quality and chain of custody

Every lot of Vesugen is synthesized in registered facilities, with independent analytical verification by third-party laboratories and full chain-of-custody documentation. The certificate of analysis (COA) for each lot can be reviewed before purchase, recording HPLC purity and the other quality-control parameters used to release the material.

Reconstitution and laboratory handling

As a bench procedure, the lyophilized vial is reconstituted with a known volume of a suitable solvent, added along the inner wall of the vial, followed by gentle swirling until fully dissolved, without vigorous shaking. The reconstituted solution should be kept refrigerated and protected from light, and used in controlled assays within the stability period validated by the laboratory. Handling must be performed only by qualified personnel, in a bench environment suitable for in vitro experimentation, with lot number and storage conditions documented according to good laboratory practice.

Frequently asked questions

What is the purity of the Vesugen supplied?

≥98% by HPLC, with the lot-specific value reported on the certificate of analysis (COA).

Is Vesugen the same as Lys-Glu-Asp (KED)?

Yes. Vesugen is the common name for the tripeptide L-Lys-L-Glu-L-Asp, identified by PubChem CID 87571363 and the molecular formula C15H26N4O8.

How should the compound be stored?

At -20 °C, protected from light and moisture, as a lyophilized powder until reconstitution.

Does the certificate of analysis come with the lot?

Yes, every lot has a matching COA that can be verified before purchase using the button on this page.

Who can purchase Vesugen?

Sales are restricted to qualified researchers and institutions, for laboratory use only, as detailed in the research-use-only notice on this page.

See the peptide reference guide, the page on how every lot is tested by HPLC and COA and the molecular structure in the PubChem database.

Research use only (RUO). This material is supplied for in vitro laboratory research only. It is not a drug, dietary supplement or cosmetic, and it is not intended for human or veterinary use, or for the diagnosis or treatment of any condition. Sales are restricted to researchers and institutions.