SLU-PP-332 5 mg

SLU-PP-332 for research: identity and specifications

SLU-PP-332 (4-hydroxy-N’-(naphthalen-2-ylmethylene)benzohydrazide, CAS 303760-60-3) is a synthetic small molecule studied as a pan-agonist of the estrogen-related receptors (ERRα, ERRβ and ERRγ). Supplied as a 5 mg vial of powder, with no fillers, carriers or excipients, at ≥98% purity by HPLC, with the lot-specific value reported on the certificate of analysis.

Scientific background

The estrogen-related receptors are nuclear receptors that regulate genes involved in mitochondrial biogenesis and oxidative metabolism. In experimental models, SLU-PP-332 is investigated as a tool compound to examine how ERR activation affects mitochondrial function, oxidative gene programs and metabolic signaling in cultured cells and in rodents.

Preclinical literature uses SLU-PP-332 in studies of skeletal muscle oxidative capacity, cellular energy metabolism and nuclear receptor biology, always under controlled bench conditions and without extrapolating results to human or veterinary use.

• ERRα, ERRβ and ERRγ agonist activity in reporter assays
• Mitochondrial biogenesis and oxidative gene expression in cell culture
• Skeletal muscle oxidative metabolism in rodent models
• Nuclear receptor signaling and metabolic regulation

Technical specifications

Analytical quality and chain of custody

Every lot of SLU-PP-332 is synthesized in registered facilities, with independent analytical verification by third-party laboratories and full chain-of-custody documentation. The certificate of analysis (COA) for each lot can be reviewed before purchase, recording HPLC purity and the other quality-control parameters used to release the material.

Reconstitution and laboratory handling

As a bench procedure, the powder is dissolved in a solvent suited to the assay (for example DMSO for in vitro work), using a volume calculated for the target concentration of the experimental design, followed by gentle mixing until fully dissolved. Stock solutions should be kept refrigerated or frozen, protected from light, and used within the stability period validated by the laboratory. Handling must be performed only by qualified personnel wearing appropriate personal protective equipment, in a bench environment suitable for in vitro experimentation, with lot number and storage conditions documented according to good laboratory practice.

Frequently asked questions

What is the purity of the SLU-PP-332 supplied?

≥98% by HPLC, with the lot-specific value reported on the certificate of analysis (COA).

Is SLU-PP-332 a peptide?

No. Despite being catalogued with peptide research reagents, SLU-PP-332 is a small synthetic molecule (C18H14N2O2), identified by PubChem CID 5338394 and CAS 303760-60-3.

How should the compound be stored?

At -20 °C, protected from light and moisture, as a powder until reconstitution.

Does the certificate of analysis come with the lot?

Yes, every lot has a matching COA that can be verified before purchase using the button on this page.

Who can purchase SLU-PP-332?

Sales are restricted to qualified researchers and institutions, for laboratory use only, as detailed in the research-use-only notice on this page.

See the peptide reference guide, the page on how every lot is tested by HPLC and COA and the molecular structure in the PubChem database.

Research use only (RUO). This material is supplied for in vitro laboratory research only. It is not a drug, dietary supplement or cosmetic, and it is not intended for human or veterinary use, or for the diagnosis or treatment of any condition. Sales are restricted to researchers and institutions.